Extended Adjuvant Endocrine Therapy for Postmenopausal Women: Treating Many to Benefit a Few
نویسندگان
چکیده
منابع مشابه
Adjuvant endocrine therapy for postmenopausal women with early breast cancer.
Results from multiple clinical trials involving aromatase inhibitors have added to the knowledge base relating to endocrine therapy of postmenopausal women with hormone receptor-positive early breast cancer. In the extended adjuvant setting, data from the Austrian Breast and Colorectal Cancer Study Group 6a trial showed an advantage for anastrozole following 5 years of tamoxifen treatment, cons...
متن کاملAdjuvant endocrine therapy for postmenopausal women with early stage breast cancer
†Author for correspondence 1Clinical Trial Coordinator, Cancer Research UK Clinical Trials Unit, Institute for Cancer Studies, The University of Birmingham, B15 2TT, UK Tel: +44 121 414 3797 Fax: +44 121 414 3700 [email protected] 2Senior Lecturer in Medical Oncology, Cancer Research UK Clinical Trials Unit, Institute for Cancer Studies, The University of Birmingham, B15 2TT, UK Tel: +44 121...
متن کاملCommentary: optimal adjuvant endocrine therapy of postmenopausal breast cancer.
There is a growing body of evidence that the optimal adjuvant endocrine therapy for hormone-sensitive breast cancer in postmenopausal women should include an aromatase inhibitor. However, further research is required to establish the optimal aromatase inhibitor and whether such a drug should be used as monotherapy or in sequence after 2 to 3 years of tamoxifen.
متن کاملAdvances in adjuvant hormonal therapy for postmenopausal women.
INTRODUCTION Since George Beatson and A. Schinzinger produced remissions of advanced breast cancer by performing bilateral oophorectomy in premenopausal patients more than 100 years ago, the effect of antihormonal therapy on breast cancer has been known. Initial endocrine therapy included oophorectomy, hypophysectomy, and adrenalectomy. The latter two were abandoned when tamoxifen citrate was a...
متن کاملAdjuvant Endocrine Therapy for Premenopausal Women With Early Breast Cancer
From the Division of Medical Oncology, Department of Medicine, European Institute of Oncology, Milan, Italy; International Breast Cancer Study Group Coordinating Center, Bern; Oncology Institute of Southern Switzerland, Bellinzona & Lugano, Switzerland; International Breast Cancer Study Group Statistical Center, Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 2017
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djx142